BT8302 APPLIED THERMODYNAMICS FOR
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BT8302 APPLIED THERMODYNAMICS FOR BIOTECHNOLOGISTS
UNIT I THERMODYNAMIC LAW AND PROPERTIES OF FLUIDS
First Law of thermodynamics, a generalized balance equation
and conserved quantities,Volumetric properties of fluids exhibiting non ideal
behavior; residual properties; estimation of thermodynamic properties using equations of state;
calculations involving actual property exchanges; Maxwell’s relations and applications.
UNIT II SOLUTION THERMODYNAMICS
Partial molar properties; concepts of chemical potential and
fugacity; ideal and non-ideal solutions concepts and applications of excess properties of mixtures;
activity coefficient; composition models; Gibbs Duhem equation.
UNIT III PHASE EQUILIBRIA
Criteria for phase equilibria; VLE calculations for binary
and multi component systems; liquid-liquid equilibria and solid-solid equilibria.
UNIT IV CHEMICAL REACTION EQUILIBRIA
Equilibrium criteria for homogeneous chemical reactions;
evaluation of equilibrium constant; effect of temperature and pressure on equilibrium constant;
calculation of equilibrium conversion and
yields for single and multiple reactions.
UNIT V THERMODYNAMIC DESCRIPTION OF MICROBIAL GROWTH AND
PRODUCT FORMATION
Thermodynamics of microbial growth stoichiometry
thermodynamics of maintenance, Calculation of the Operational Stoichiometry of a growth process at
Different growth rates, Including Heat using the Herbert –Pirt Relation for Electron Donor,
thermodynamics and stoichiometry of Product Formation
TEXT BOOKS:
1. Smith J.M., Van Ness H.C., and Abbot M.M. “Introduction
to Chemical Engineering Thermodynamics”, VIth Edition. Tata McGraw-Hill, 2003.
2. Narayanan K.V. “A Text Book of Chemical Engineering
Thermodynamics”, PHI, 2003.
3. Christiana D. Smolke, “ The Metabolic Pathway Engineering
Handbook Fundamentals”, CRC Press Taylor & Francis Group, 2010.
REFERENCE:
1. Sandler S.I. “Chemical and Engineering Thermodynamics”,
John Wiley,1989
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